Principal Investigator:
Jan Hasenauer
, (1)Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health, (2)Center for Mathematics, Technische Universität München, (3)Faculty of Mathematics and Natural Sciences, University of Bonn
HPC Platform used:
SuperMUC and SuperMUC-NG of LRZ
Local Project ID:
pr62li
Computational mechanistic modelling using systems of ordinary differential equations (ODE) has become an integral tool in systems biology. Parameters of such models are often not known in advance and need to be inferred from experimental data, which is computationally very expensive. The SuperMUC supercomputer enabled researchers from the Helmholtz Zentrum Munich to evaluate state-of-the-art algorithms and to develop novel, more efficient algorithms for parameter estimation from large datasets and relative measurements.
