Life Sciences

Principal Investigator: Ilpo Vattulainen , Department of Physics, Tampere University of Technology (Finland)

HPC Platform used: Hermit of HLRS

Local Project ID: PP12071362

Scientists from the Tampere University of Technology, Finland, have shown the profound importance of glycosylation in membrane receptor conformation. The researchers used extensive atomistic simulations together with biochemical experiments to show for EGFR that receptor conformation depends in a critical manner on its glycosylation.